Consortium
Co-ordinators: The University of Manchester
Principal Investigator
Professor Sabine Flitsch
Professor of Chemical Biology
Sabine’s interests lie in the use of a high-throughput glycan array mass spectrometry screening platform for study of glycoenzyme activities.
Professor Nicholas Turner
Professor of Chemical Biology
Nick brings considerable expertise in using synthetic biology to produce designer enzymes with tailored characteristics/specificities.
Project Management
Dr. Hannah Roberts
Scientific Project Manager
Hannah is primarily involved in the overall management of the grant with particular focus on the commercialisation of results.
Postdoctoral Scientist
Dr. Peter Both
Research Associate
Peter is working on the discovery of glycozymes for biosynthesis and functional studies of medically-relevant glycans.
Academic Project Partner: John Innes Centre
Principal Investigator
Professor Rob Field
Professor of Chemical Biology
Expertise in the development and application of tool-kits of glycoenzyme inhibitors, spectroscopic and mass spectrometric techniques in order to better understand and exploit carbohydrate-active enzymes.
Postdoctoral Scientist
Dr Giulia Pergolizzi
Research Associate
Giulia is focusing on new enzymes to interpenetrate start-cellulose gels to produce stable enzymes for Kg scale.
Academic Project Partner: Institute of Food Research
Principal Investigator
Dr Nathalie Juge
Research Leader
Natalie has worked extensively on glycoenzymes involved in cell wall degradation and currently has a strong interest in glycosidases in the gut microbiome.
Postdoctoral Scientist
Dr Devon Kavanaugh
Research Associate
Devon is focusing on mucin-degrading enzymes in gut bacteria.
Academic Project Partner: The University of Newcastle
Principal Investigator
Dr David Bolam
Senior Lecturer
David studies the molecular mechanisms utilised by our resident gut bacteria to recognise, acquire and degrade complex glycans.
Postdoctoral Scientist
Dr Lucy Crouch
Research Associate
Lucy is looking at PULs associated with N-glycan and/or O-glycan degradation
Industry Project Partner: Ludger Ltd.
Principal Investigator
Dr Daniel Spencer
Head of Development
Ludger are testing the efficacy of the glycoenzymes for use in diagnostic test kits and for commercialisation as well as designing and curating the glycoenzymes database.
Industry Project Partner: Biocatalysts Ltd.
Principal Investigator
Dr Andrew Ellis
Technical Director
Biocatalysts interest lie in enzymes for the production/functionalisation of food and beverages.
Subcontractor: Prozomix Ltd.
Principal Investigator
Dr Simon Charnock
Managing Director
Prozomix supply the discovery and production of novel enzymes for validation by academic partners.