Co-ordinators: The University of Manchester
Professor Sabine Flitsch
Sabine’s interests lie in the use of a high-throughput glycan array mass spectrometry screening platform for study of glycoenzyme activities.
Professor Nicholas Turner
Nick brings considerable expertise in using synthetic biology to produce designer enzymes with tailored characteristics/specificities.
Dr. Syed Ahmed
Scientific Project Manager
Syed is primarily involved in the overall management of the grant with a particular focus on the commercialisation of results.
Dr. Peter Both
Peter is working on the discovery of glycozymes for biosynthesis and functional studies of medically-relevant glycans.
Academic Project Partner: John Innes Centre
Professor Rob Field
Expertise in the development and application of tool-kits of glycoenzyme inhibitors, spectroscopic and mass spectrometric techniques in order to better understand and exploit carbohydrate-active enzymes.
Dr Giulia Pergolizzi
Giulia is focusing on new enzymes to interpenetrate start-cellulose gels to produce stable enzymes for Kg scale.
Academic Project Partner: Institute of Food Research
Dr Nathalie Juge
Natalie has worked extensively on glycoenzymes involved in cell wall degradation and currently has a strong interest in glycosidases in the gut microbiome.
Dr Didier Ndeh
Didier is focusing on mucin-degrading enzymes in gut bacteria.
Academic Project Partner: The University of Newcastle
Dr David Bolam
David studies the molecular mechanisms utilised by our resident gut bacteria to recognise, acquire and degrade complex glycans.
Dr Lucy Crouch
Lucy is looking at PULs associated with N-glycan and/or O-glycan degradation
Industry Project Partner: Ludger Ltd.
Dr Daniel Spencer
Ludger are testing the efficacy of the glycoenzymes for use in diagnostic test kits and for commercialisation as well as designing and curating the glycoenzymes database.
Industry Project Partner: Biocatalysts Ltd.
Dr Andrew Ellis
Biocatalysts interest lie in enzymes for the production/functionalisation of food and beverages.
Subcontractor: Prozomix Ltd.
Dr Simon Charnock
Prozomix supply the discovery and production of novel enzymes for validation by academic partners.